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Codeine -

: It is often paired with non-opioids like acetaminophen or ibuprofen to enhance pain relief through synergistic effects. Common Side Effects

: Effectiveness varies significantly between individuals. Some are "ultra-rapid metabolizers" who convert codeine too quickly, leading to potentially toxic morphine levels, while others may feel no effect at all because their bodies cannot process the drug.

While effective, codeine commonly causes several adverse reactions: Codeine - StatPearls - NCBI Bookshelf - NIH

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