Disruptions in these pathways have significant effects on brain function, particularly in the hippocampus:
The name likely refers to a specific compressed data part related to a scientific study on the Retinoic Acid Receptor (RAR) and its complex interactions with the Retinoid X Receptor (RXR) , commonly referred to as the RAR/RXR signaling pathway . FrSi_TCRSR.part5.rar
: Some RAR types can cell-specifically override others, creating artificial redundancies often observed in gene disruption studies. 4. Pathophysiological Implications (Diabetes and Cancer) Disruptions in these pathways have significant effects on
The RXR–RAR–DR5 complex is a primary driver of gene expression. This complex functions through: FrSi_TCRSR.part5.rar
: Dysfunction in the RAR/RXR pathway can lead to the downregulation of RARβ , causing impairments in AMPA-mediated synaptic transmission and long-term potentiation (LTP).