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: Detailed overviews are available from the Cleveland Clinic and StatPearls (NIH) . Science & Climate

LAST is a life-threatening reaction that occurs when local anesthetic medications enter the bloodstream in toxic amounts, primarily affecting the central nervous and cardiovascular systems. : Detailed overviews are available from the Cleveland

: High doses of anesthetics like bupivacaine or specific injection techniques increase the risk. : Detailed overviews are available from the Cleveland