The core of the episode is the hypocrisy surrounding "gross-out" humor. While society (and South Park itself) has long celebrated farts as comedy gold, "queefing" is met with visceral disgust.

If there is one thing South Park excels at, it’s taking a juvenile concept and stretching it into a sharp social commentary. Season 13, Episode 4, is the poster child for this approach. Originally airing on April 1, 2009 , the episode serves as both a literal April Fool’s prank on the audience and a biting look at gender-based double standards in comedy. The Plot: A Prank Within a Prank

The boys of South Park are buzzing with anticipation for the second part of a cliffhanger episode of their favorite show, Terrance and Phillip . Instead, the network pulls a fast one, replacing it with a new show called The Queef Sisters .