Difference A Day Makes | [s5e22] What A

: George O'Malley faces an emotional crisis when almost all the students from the accident die under his care, leaving him devastated until Owen Hunt helps him see the lives he did save.

While the wedding takes center stage, the hospital remains in chaos due to a tragic car crash involving college students on their way to graduation. [S5E22] What a Difference a Day Makes

In , the Season 5, Episode 22 milestone titled " What a Difference a Day Makes " is a landmark 100th episode that originally aired on May 7, 2009. It is widely celebrated for its emotional depth, shifting from a planned grand wedding for Meredith and Derek to a poignant ceremony for Izzie Stevens and Alex Karev. The Unexpected Wedding : George O'Malley faces an emotional crisis when

: Despite the shift in plans, the wedding remains a fan favorite, featuring the original "MAGIC" interns (Meredith, Alex, George, Izzie, and Cristina) as the wedding party. It is widely celebrated for its emotional depth,

: To promote the 100th episode, ABC created a real wedding website for Meredith and Derek that fans could actually visit and RSVP to.